FEN-PHEN
Chemical Structure phenterminechemicalstructure
fenfluraminechemicalstructure
Drug Class Combined monoaminergic anorectic (5-HT/DA dual system)
Mechanisms of Action Fenfluramine limb: Serotonin release (SERT reversal) Satiety induction via hypothalamic 5-HT2C activation

Phentermine limb: Dopamine/norepinephrine reuptake inhibition Psychostimulant-driven appetite suppression
Monograph Combination: Fenfluramine (5-HT releaser) + Phentermine (DA/NE releaser)

Function: Bi-molecular anorectic engineered for synergistic weight suppression

Withdrawal: Removed from market (1997) due to valvulopathy and pulmonary hypertension risks

Modern Interest: Repurposed in CNS pharmacology and oncological metabolic modulation research

Speculative Status: Therapeutically dead but biochemically undead — a post-market neuropharmacological archetype

Full Monograph.
Synthesis Batch Initiated Target: 4.20 grams (actives: phentermine 1.5 g ; fenfluramine 2.7 g) Batch Details;
| Amount acquired for synthesis: 2.10 grams
| Amount acquired for speculative holding: 0 mg
Note: These figures reflect documented theoretical acquisitions. Updated manually.
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  • 2 Pellets (individual actives: phentermine 75mg+fenfluramine 135mg) x 10 @ 10 EUR
  • 2 Pellets (individual actives: phentermine 75mg+fenfluramine 135mg) x 10 @ 8 EUR

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