(D)-Deprenyl

CHEMICAL STRUCTURE
DRUG CLASS	SELECTIVE MAO-B INHIBITOR / PROTOPSYCHOSTIMULANT
MECHANISMS OF ACTION	IRREVERSIBLE MONOAMINE OXIDASE-B INHIBITION (MAO-B) INCREASES SYNAPTIC DOPAMINE, PHENYLETHYLAMINE (PEA), AND TYRAMINE LEVELS AT HIGHER DOSES, EXHIBITS NON-SELECTIVE MAO INHIBITION AND STIMULANT EFFECTS TRACE AMINE RECEPTOR (TAAR1) INTERACTION SUSPECTED
MONOGRAPH	CHEMICAL NAME: (2S)-N-methyl-1-phenyl-N-prop-2-ynyl-propan-2-amine DEVELOPMENT: INTRODUCED IN 1960S AS AN ANTIDEPRESSANT, NOW USED IN PARKINSON'S DISEASE AT LOW DOSES, ENHANCES DOPAMINERGIC TONE IN SUBCORTICAL BRAIN REGIONS AT HIGH DOSES, CAUSES PSYCHOSTIMULANT-LIKE EFFECTS DUE TO MAO-A INHIBITION AND INCREASED PEA MODERN INTEREST: ENTHEODELIC POTENTIAL IN LOW-DOSE MICROSTACKS. A VINTAGE MONOAMINE NOW REINTERPRETED BY PSYCHOPHARMACEUTICAL THEORISTS. STRUCTURAL NOTES: CONTAINS PROPYNYLAMINE CHAIN → ALKYNE-BEARING MAO INHIBITORS MAY FORM IRREVERSIBLE COVALENT BONDS FULL MONOGRAPH.
SYNTHESIS BATCH INITIATED	300 MILIGRAMS TARGET \| AMOUNT ACQUIRED FOR SYNTHESIS PURPOSES: 300 MG \| AMOUNT ACQUIRED FOR SPECULATIVE HOLDING: 0 MG NOTE: THESE FIGURES REFLECT TOTAL DOCUMENTED ACQUISITIONS. UPDATED MANUALLY
ORDER BOOK	OFFER 25MG X 3 @ 0.22 EUR 50MG X 3 @ 0.18 EUR 50MG X 2 @ 0.14 EUR 50MG X 2 @ 0.12 EUR 25MG X 3 @ 0.10 EUR 25MG X 3 @ 0.08 EUR 25MG X 3 @ 0.06 EUR BID NO BIDS
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