3-BENZHYDRYLMORPHOLINE
| CHEMICAL STRUCTURE |  |
|---|---|
| DRUG CLASS | NOVEL MORPHOLINE HYBRID DERIVATIVE |
| MECHANISMS OF ACTION |
CNS STIMULANT AND ANORECTIC STRUCTURALLY RELATED TO PIPRADROL AND PHENMETRAZINE. DOPAMINE - NOREPINEPHRINE REUPTAKE INHIBITION (DNRI) LIKE DESOXYPIPRADROL AND PIPRADROL, WHICH ALSO FEATURE A BENZHYDRYL CORE, 3-BENZHYDRYLMORPHOLINE LIKELY BINDS TO AND INHIBITS THE DOPAMINE TRANSPORTER (DAT) AND NOREPINEPHRINE TRANSPORTER (NET), PREVENTING REUPTAKE AND INCREASING EXTRACELLULAR CONCENTRATIONS OF THESE MONOAMINES. |
| MONOGRAPH |
CHEMICAL NAME: 3-(DIPHENYLMETHYL)MORPHOLINE DEVELOPMENT: CREATED BY AMERICAN HOME PRODUCTS IN THE 1950S. EXHIBITS STIMULANT AND APPETITE-SUPPRESSANT PROPERTIES AS A LIPOPHILIC AMINE, LIKELY CROSSES THE BLOOD-BRAIN BARRIER, WITH METABOLISM POSSIBLY INVOLVING HEPATIC CYTOCHROME SYSTEMS STRUCTURAL INTEREST: AMONG NOVEL MORPHOLINE DERIVATIVES EXPLORED FOR STIMULANT OR ANORECTIC USE IN MID-20TH CENTURY. MODERN INTEREST: COULD SERVE AS A CHEMICAL SCAFFOLD FOR DESIGNING CNS-ACTIVE AGENTS IT SHOWS STIMULANT/ANORECTIC PROPERTIES IN CONCEPT, IT'S A CHEMICAL CURIOSITY OF INTEREST PRIMARILY TO MEDICINAL CHEMISTS. |
| SYNTHESIS BATCH INITIATED | 1 GRAM TARGET | AMOUNT ACQUIRED FOR SYNTHESIS PURPOSES: 0 MG | AMOUNT ACQUIRED FOR SPECULATIVE HOLDING: 0 MG NOTE: THESE FIGURES REFLECT TOTAL DOCUMENTED ACQUISITIONS. UPDATED MANUALLY |
| ORDER BOOK |
OFFER
BID
|
| ORDER VIA | (ONLY TO EUROPE, EXCEPT UK, DENMARK, GERMANY AND AUSTRIA.) |