Chemical Structure
chemicallstructure
Drug Class
Novel morpholine hybrid derivative
Mechanisms of action
CNS stimulant and anorectic structurally related to pipradrol and phenmetrazine.
Dopamine - norepinephrine reuptake inhibition (DNRI)
Like desoxypipradrol and pipradrol, which also feature a benzhydryl core, 3-Benzhydrylmorpholine likely binds to and inhibits the dopamine transporter (DAT) and norepinephrine transporter (NET), preventing reuptake and increasing extracellular concentrations of these monoamines.
Monograph
Chemical Name: 3-(Diphenylmethyl)morpholine
Development: Created by American Home Products in the 1950s.
Exhibits stimulant and appetite-suppressant properties
As a lipophilic amine, likely crosses the blood-brain barrier, with metabolism possibly involving hepatic cytochrome systems
Structural Interest: Among novel morpholine derivatives explored for stimulant or anorectic use in mid - 20th century.
Modern Interest: Could serve as a chemical scaffold for designing CNS-active agents
It shows stimulant/anorectic properties in concept, its a chemical curiosity of interest primarily to medicinal chemists.

Full Monograph.

Synthesis batch initiated
1 gram target
|Amount acquired for synthesis purposes: 0 mg
|Amount acquired for speculative holding: 0 mg
Note: These figures reflect total documented acquisitions. Updated manually
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